So, it could be considered as a safe and more cost-effective therapeutic agent for clinical treatment of bone disorders.Īrvidson K, Abdallah B, Applegate L, Baldini N, Cenni E, Gomez-Barrena E, et al. According to this finding, Symphytum officinale as a natural compound can significantly induce osteogenic differentiation of rat BM-MSCs. The results illustrated that Symphytum 6 C had the most osteogenic induction effect compare with osteogenic standard medium. In the present study, the ability of homeopathic remedy Symphytum officinale to induce osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells (rat BM-MSCs) was studied. Lay SummaryĬell therapy has been proposed as an effective treatment method for bone regeneration using stem cells and osteogenic inducting mediators. ConclusionsĪccording to this finding, Symphytum could enhance osteogenic differentiation of MSCs and can be considered as a safe, low cost, and highly effective drug for bone regeneration. Also, quantitative analyses of ALP activity revealed that Symphytum 6 C caused the most increase in the ALP activity up to 4.04 ± 0.34 and 7.86 ± 1.38 on day 7 and 21, respectively. Symphytum 6 C had the most color intensity in ALZ and ALP staining assays. MTT assay results illustrated that Symphytum 200 C had a high cytotoxicity (to about 75.2 ± 3.12), so that lower potencies were used for the next experiments. The osteogenic induction ability of Symphytum has been assessed by alizarin red staining (ALZ) and quantitative alkaline phosphatase (ALP) activity assays and compared with the osteogenic standard medium. Cytotoxic effect of Symphytum on the MSCs was evaluated by MTT assay. MSCs were isolated from the rat’s bone morrow. In the present study, the ability of homeopathic remedy Symphytum officinale to induce osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells (rat BM-MSCs) was studied Methods Your doctor will decide if your condition can only be treated by homeopathy or if your treatment should be supplemented with allopathy.Cell therapy has been proposed as an effective treatment method for bone regeneration using stem cells and osteogenic inducting mediators. Some diseases can not be treated by homeopathy simply by self-medication. What to do if there is no improvement within 24 hours In chronic conditions, the low dilution remedies (> to 9CH) are taken 1-2 times a day, the substantive remedies are taken 1 time a week or once a month 1. Therefore, we must space out, 3 or 4 times a day, then gradually stop. In acute conditions, it is advisable to take homeopathic remedies every hour until symptoms improve. Homeopathic medicines have no chemical toxicity or against indication or interaction with other drugs, nor adverse reaction to the amount of product ingérée.Les pregnant women can heal without known risk for them and their future child but it is best to seek advice. The granules are very slow to dissolve, it is necessary to prepare in advance your mix. The homeopathic granules are dissolved in 100ml of water. Leave homeopathic granules for babies and children Keep homeopathic medicines away from light, heat, moisture. To eaC tube of color corresponds dilutionĤCH 5CH red yellow green blue 7CH 9 green water CH 12CH 15C orange purple 30c Tube translucent granules (used to display the remaining granules). Use a toothpaste without mint (type Homéodent Boiron). It is advisable not to touC the fingers homeopathic granules.ĭo not swallow the astringent substances in the half hour before taking homeopathic medicines suC as coffee, tobacco, camphor, mint and chamomile. Turn the tube to bring down the required number of granules in the cap and remove the pellets under the tongue. The homeopath chooses the appropriate dilution and dosage to the patient's health status and characteristic symptoms. Homeopathic medicines can be used in various symptoms, so it is not possible to determine the indications and dosage of a specific preparation. SYMPHYTUM OFFICINALE 4C 9C 15C 30C 7C 5C granules homeopathy BoironĬNAM Code: 7071705700020200 Indications and Dosage

Boiron symphytum